Dr Paul Harden trained for six years as a nephrologist and transplant physician at the Western Infirmary in Glasgow. Subsequently, he worked as a Consultant Nephrologist with a special interest in transplantation at the University Hospital of North Staffordshire. During this period, he developed an interest in non-adherence in young adult transplant recipients and transition of care from paediatric to adult care. He established a joint transition process with Birmingham Children’s Hospital.

In 2002, Dr Harden joined the Oxford Kidney Unit and Transplant Centre and has continued to pursue his interest in transition, having established joint clinics with Great Ormond Street and Evelina Children’s Hospitals in London. He has been clinical advisor to the National Health Service in the UK on adolescent transition and young adult services in patients with ESRD. He runs a unique community-based young adult transplant service in Oxford. He was appointed as an Associate Professor of Medicine at UCT, South Africa in 2019 in view of his teaching and development partnership with the Red Cross Hospital and Groote Schuur Hospital.

In addition, Paul Harden is interested in malignancy post-transplantation and the impact of targeted immunosuppression reduction. He is Chief Investigator of the RESCUE (UK) trial of immunosuppression modulation for squamous cell skin cancer post-transplantation. He is currently working on a series of trials of cell therapy to allow immunosuppression reduction utilising autologous T regulatory cells.